Figures & data
Figure 1. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced global m6A RNA methylation changes. CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.
![Figure 1. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced global m6A RNA methylation changes. CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.](/cms/asset/c6f0affd-bce7-4236-982c-65f4f9e97195/kepi_a_2294515_f0001_b.gif)
Figure 2. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the μ-opioid receptor gene (OPRM1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.
![Figure 2. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the μ-opioid receptor gene (OPRM1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.](/cms/asset/bc26f08c-e71b-4e69-9249-03029390999e/kepi_a_2294515_f0002_b.gif)
Figure 3. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the δ-opioid receptor gene (OPRD1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.
![Figure 3. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the δ-opioid receptor gene (OPRD1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.](/cms/asset/e2ae4b5e-a70a-4ee5-94cc-5b3049c98956/kepi_a_2294515_f0003_b.gif)
Figure 4. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the κ-opioid receptor gene (OPRK1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.
![Figure 4. Chronic intermittent ethanol (CIE) exposure/withdrawal-induced mRNA methylation and expression changes in the κ-opioid receptor gene (OPRK1). CTL: Control SH-SY5Y or SW620 cells (without ethanol exposure). CIE: a 3-week chronic intermittent ethanol (CIE) exposure. CIE+WD: a 3-week chronic intermittent ethanol exposure followed a 24-hr ethanol withdrawal.](/cms/asset/4dc71b0f-75a1-43e9-86a5-b91e033a57c0/kepi_a_2294515_f0004_b.gif)
Supplementary Materials 20231118.docx
Download MS Word (1.5 MB)Data availability statement
The data that support the findings of this study are available upon request from the corresponding author, HZ.