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Research Article

Calling the question: what is mammalian transgenerational epigenetic inheritance?

, , , &
Article: 2333586 | Received 18 Dec 2023, Accepted 17 Mar 2024, Published online: 25 Mar 2024

Figures & data

Figure 1. (a) Summation of the number of papers reviewed that met each of the different specified criteria necessary for TEI qualification. A total of 80 papers were analysed for each TEI criteria category. Criteria on the x-axis include 1 = inheritance of phenotypes; 2 = inheritance of epigenetic marks; 3 = inheritance of the same epimutations; 4 = gene expression changes across generations; and 5 = germ cell tested in each generation. The numbers above each column depict the total number of papers that met the qualifications for that criteria category. (b) Summation of the number of total TEI criteria that were met per paper reviewed. The x-axis indicates the total number of criteria that were satisfied per paper, ranging from 0 (no criteria met) to 5 (all criteria met). The numbers above each column depict the total number of papers that met that number of criteria.

Figure 1. (a) Summation of the number of papers reviewed that met each of the different specified criteria necessary for TEI qualification. A total of 80 papers were analysed for each TEI criteria category. Criteria on the x-axis include 1 = inheritance of phenotypes; 2 = inheritance of epigenetic marks; 3 = inheritance of the same epimutations; 4 = gene expression changes across generations; and 5 = germ cell tested in each generation. The numbers above each column depict the total number of papers that met the qualifications for that criteria category. (b) Summation of the number of total TEI criteria that were met per paper reviewed. The x-axis indicates the total number of criteria that were satisfied per paper, ranging from 0 (no criteria met) to 5 (all criteria met). The numbers above each column depict the total number of papers that met that number of criteria.
Supplemental material

Supplementary Table 1.docx

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Data availability statement

The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.