DNA methylation in people with anorexia nervosa: Epigenome-wide patterns in actively ill, long-term remitted, and healthy-eater women

Figures & data

Table 1. Sample characteristics.

Variable	AN-active (n = 145)	AN-remitted (n = 49)	NED (n = 64)
Age (M ± SD)^†	24.73 (7.4)^a	27.39 (6.2)^b	24.50 (5.4)^a
BMI (M ± SD)^‡	15.05 (1.8)^a	21.86 (2.7)^b	22.59 (2.6)^b
Cigarette smoker, n (%)	30 (20.7%)	5 (10.2%)	7 (10.9%)
Psychotropic medication use, n (%)^‡	94 (64.8%)^a	17 (34.7%)^b	0 (0%)^c
AN subtype:
AN-R, n (%)	70 (48.3%)	N/A	N/A
AN-BP, n (%)	75 (51.7%)
Chronicity in months (SD)	95.63 (87.6)	98.69 (61.2)	N/A
EDE-Q
Global EDE-Q^‡	3.93 (1.2)^a	1.04 (0.8)^b	0.42 (0.5)^c
Restraint^‡	3.93 (1.7)^a	0.59 (0.8)^b	0.28 (0.6)^b
Eating Concern^‡	3.03 (1.4)^a	0.47 (0.8)^b	0.14 (0.4)^b
Shape Concern^‡	4.58 (1.2)^a	1.65 (1.3)^b	0.75 (0.8)^c
Weight concern^‡	4.16 (1.5)^a	1.41 (1.1)^b	0.51 (0.7)^c

Note: Means with different letters in their superscripts differed at p < 0.05.

^†p < 0.05; ^‡p = 0.001

AN: anorexia nervosa; NED: non-eating-disordered; BMI: body mass index; AN-R: anorexia nervosa, restricting type; AN-BP: anorexia nervosa, binge-eating/purging type; EDE-Q: Eating Disorder Examination Questionnaire; AN-active, n = 123; AN-remitted, n = 40; NED, n = 60. Chronicity, n = 144.

Data availability statement

Data upon which this study were based are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.