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Articles

Clinical utility of the updated European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and the Mycoses Study Group Education and Research Consortium computed tomography criteria of invasive pulmonary aspergillosis in hematological malignancies

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Figures & data

Figure 1. 66-year-old male with chronic lymphocytic leukemia, presenting with crepitations over the lung, cough and fever. High resolution CT scan obtained at level of pulmonary veins shows massive segmental consolidations with air bronchogram located in both lungs (black narrow arrows), nodules with halo sign (white narrow arrow) in lingular segment in left lung and free fluid in right pleural cavity (black wide arrow).

Figure 1. 66-year-old male with chronic lymphocytic leukemia, presenting with crepitations over the lung, cough and fever. High resolution CT scan obtained at level of pulmonary veins shows massive segmental consolidations with air bronchogram located in both lungs (black narrow arrows), nodules with halo sign (white narrow arrow) in lingular segment in left lung and free fluid in right pleural cavity (black wide arrow).

Figure 2. 35-year-old male with acute myeloid leukemia presenting with dry cough. High resolution CT obtained at level of pulmonary veins shows wedge-shape consolidations located in lingular segment in left lung (black narrow arrow). Nodule in the middle lobe of the right lung (white narrow arrow).

Figure 2. 35-year-old male with acute myeloid leukemia presenting with dry cough. High resolution CT obtained at level of pulmonary veins shows wedge-shape consolidations located in lingular segment in left lung (black narrow arrow). Nodule in the middle lobe of the right lung (white narrow arrow).

Table 1. HRCT acquisition parameters.

Figure 3. 40-year-old female with cutaneous T-cell lymphoma presenting with fever and dyspnea. High resolution CT scans obtained at level of lower lobes shows consolidations (black narrow arrow) and multiple nodules with halo sign located in both lungs (white narrow arrow).

Figure 3. 40-year-old female with cutaneous T-cell lymphoma presenting with fever and dyspnea. High resolution CT scans obtained at level of lower lobes shows consolidations (black narrow arrow) and multiple nodules with halo sign located in both lungs (white narrow arrow).

Table 2. Characteristics of pulmonary findings.

Figure 4. 72-year-old woman with acute myeloid leukemia presenting with fever. High- resolution CT scan obtained at level of main bronchi shows micronodules and nodules located peripherally in middle right lobe (black narrow arrow).

Figure 4. 72-year-old woman with acute myeloid leukemia presenting with fever. High- resolution CT scan obtained at level of main bronchi shows micronodules and nodules located peripherally in middle right lobe (black narrow arrow).

Figure 5. 62-year-old female with acute myeloid leukemia presenting with cough and fever. High resolution CT scan obtained at level of lower lobes shows nodules with halo sign located peripherally in right lower lobe (black narrow arrow).

Figure 5. 62-year-old female with acute myeloid leukemia presenting with cough and fever. High resolution CT scan obtained at level of lower lobes shows nodules with halo sign located peripherally in right lower lobe (black narrow arrow).

Figure 6. 56-year-old male with primary myeloid fibrosis 30 days after bone marrow transplantation presenting with fever. High resolution CT scan obtained at level of lower lobes shows peripherally located nodules with halo sign in right lower lobe (black narrow arrow).

Figure 6. 56-year-old male with primary myeloid fibrosis 30 days after bone marrow transplantation presenting with fever. High resolution CT scan obtained at level of lower lobes shows peripherally located nodules with halo sign in right lower lobe (black narrow arrow).

Figure 7. 28-year-old female with congenital neutropenia presenting with productive cough and fever. High resolution CT scans obtained at level of lower lobes shows massive consolidations with air- bronchogram located in basal segments of left lower lobe (black narrow arrow).

Figure 7. 28-year-old female with congenital neutropenia presenting with productive cough and fever. High resolution CT scans obtained at level of lower lobes shows massive consolidations with air- bronchogram located in basal segments of left lower lobe (black narrow arrow).

Figure 8. 35-year-old male with acute myeloid leukemia presenting with dry cough. High resolution CT in coronal plane shows wedge-shape consolidations located in lingular segment in left lung (black narrow arrow).

Figure 8. 35-year-old male with acute myeloid leukemia presenting with dry cough. High resolution CT in coronal plane shows wedge-shape consolidations located in lingular segment in left lung (black narrow arrow).

Figure 9. 37-year-old male with acute myeloid leukemia 26 days after bone marrow transplantation presenting with fever. High resolution CT scan obtained at level of lower lobes shows peripherally located nodules and micronodules with halo sign in left lower lobe (black narrow arrow).

Figure 9. 37-year-old male with acute myeloid leukemia 26 days after bone marrow transplantation presenting with fever. High resolution CT scan obtained at level of lower lobes shows peripherally located nodules and micronodules with halo sign in left lower lobe (black narrow arrow).

Table 3. Patients characteristics.

Table 4. Characteristics of pulmonary findings.

Table 5. Location and number of lesions.

Table 6. Location of the lesions according to the number of lesions.

Data availability

The database used to support the findings of this study is available from the corresponding author upon request.