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Original Article

Distribution of advanced HIV disease from three high HIV prevalence settings in Sub-Saharan Africa: a secondary analysis data from three population-based cross-sectional surveys in Eshowe (South Africa), Ndhiwa (Kenya) and Chiradzulu (Malawi)

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Article: 1679472 | Received 31 May 2019, Accepted 20 Sep 2019, Published online: 04 Nov 2019

Figures & data

Table 1. Distribution of baseline characteristics by HIV status of 18,991 individuals who participated in the three surveys Kenya, Malawi and South Africa.

Table 2. Distribution of baseline characteristics of 3957 HIV-positive individuals by CD4 count (CD4 < 200 vs CD4 ≥ 200 cells/µl) in the three surveys Ndhiwa (Kenya), Chiradzulu (Malawi) and Eshowe (South Africa).

Table 3. Cascade of care of 385 individuals with advanced HIV disease.

Table 4. Cascade of care of 104 advanced HIV disease individuals with CD4 < 100 copies/ml (to be added to the appendix).

Figure 1. Showing distribution of 358 individuals with advanced HIV disease by ART status for each survey and overall.

(a) Kenya: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and ART prophylaxis for pregnant and breast-feeding women if CD4 > 350 cells/µl (Option A)(b) Malawi: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and lifelong ART for pregnant and breastfeeding women (Option B+)(c) South Africa: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and ART for pregnant and breastfeeding women until cessation of breastfeeding (Option B).

Figure 1. Showing distribution of 358 individuals with advanced HIV disease by ART status for each survey and overall.(a) Kenya: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and ART prophylaxis for pregnant and breast-feeding women if CD4 > 350 cells/µl (Option A)(b) Malawi: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and lifelong ART for pregnant and breastfeeding women (Option B+)(c) South Africa: ART eligibility at the time of survey was CD4 ≤ 350 cells/µl or WHO Stage 3 or 4 disease and ART for pregnant and breastfeeding women until cessation of breastfeeding (Option B).

Table 5. Distribution by time on ART for 147 individuals with advanced HIV disease on ART.

Table 6. Distribution by sex, age and viral load of 106 individuals with advanced HIV disease who had been on ART for at least 6 months.

Table 7. Crude and adjusted ORs for the effect of sex, age and ART on individuals with advanced HIV disease.