Figures & data
Figure 1. Selected features of TFV/EFV-NPs-in-film. (a) Photograph and (b, c) SEM micrographs (surface and exposed side sections after fracture; bars = 50 µm) of TFV/EFV-NPs-in-film. (d) EFV release profile in simulated vaginal fluid from TFV/EFV-film, EFV-NPs (i.e., without being incorporated into film) and TFV/EFV-NPs-in-film. Relevantly, almost half of the drug content was released within 1 h, which could provide a burst dose for immediate protection, while continuously drug release up to 24 h may aid sustaining protection. Points and vertical bars in drug release profiles represent mean values and standard deviations, respectively (n = 3). Please note the square root of time in the x-axis. Modified from [Citation14], Copyright (2016), with permission from Elsevier.
![Figure 1. Selected features of TFV/EFV-NPs-in-film. (a) Photograph and (b, c) SEM micrographs (surface and exposed side sections after fracture; bars = 50 µm) of TFV/EFV-NPs-in-film. (d) EFV release profile in simulated vaginal fluid from TFV/EFV-film, EFV-NPs (i.e., without being incorporated into film) and TFV/EFV-NPs-in-film. Relevantly, almost half of the drug content was released within 1 h, which could provide a burst dose for immediate protection, while continuously drug release up to 24 h may aid sustaining protection. Points and vertical bars in drug release profiles represent mean values and standard deviations, respectively (n = 3). Please note the square root of time in the x-axis. Modified from [Citation14], Copyright (2016), with permission from Elsevier.](/cms/asset/ce97db80-2822-436e-bc92-096332e749dc/iedd_a_1270938_f0001_oc.jpg)