Figures & data
Table 1. Comparison of single-use and reusable autoinjectors.
Figure 1. Response to Question 14 of the User Trial Questionnaire, ‘Overall experience with using injection device’ (primary endpoint).
CI, confidence interval. aDifference (95% CI) between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use. p value is based on the exact sign test of equality of paired proportions. Includes patients with complete data for both autoinjectors (N = 95).
![Figure 1. Response to Question 14 of the User Trial Questionnaire, ‘Overall experience with using injection device’ (primary endpoint).CI, confidence interval. aDifference (95% CI) between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use. p value is based on the exact sign test of equality of paired proportions. Includes patients with complete data for both autoinjectors (N = 95).](/cms/asset/98ece86d-695f-44e6-b9b7-163c24eae9aa/iedd_a_1407755_f0001_oc.jpg)
Table 2. Patient characteristics and responses to questionnaire at baseline.
Figure 2. Autoinjector ease of use by previous injection device experience.
Diff., difference between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use; the numbers in parentheses show the 95% confidence interval; PFS: prefilled syringe. p values are based on the exact sign test of equality of paired proportions. aPatients with concordant responses.
![Figure 2. Autoinjector ease of use by previous injection device experience.Diff., difference between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use; the numbers in parentheses show the 95% confidence interval; PFS: prefilled syringe. p values are based on the exact sign test of equality of paired proportions. aPatients with concordant responses.](/cms/asset/2973124b-2fa3-4a19-808f-3a8828588209/iedd_a_1407755_f0002_oc.jpg)
Figure 3. Percentages of patients rating each device as very easy or easy to use by quartiles of SDMT (a) oral and (b) written scores.
SDMT oral and written scores range from 0 to 110, with lower scores indicating cognitive deficit. Quartile 4 includes the highest values, with the least cognitive deficit. SDMT, Symbol Digit Modalities Test. aDifference between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use. bBased on exact sign test of equality of paired proportions.
![Figure 3. Percentages of patients rating each device as very easy or easy to use by quartiles of SDMT (a) oral and (b) written scores.SDMT oral and written scores range from 0 to 110, with lower scores indicating cognitive deficit. Quartile 4 includes the highest values, with the least cognitive deficit. SDMT, Symbol Digit Modalities Test. aDifference between devices (in percentage points; single-use autoinjector minus reusable autoinjector) in the proportions of patients rating each autoinjector as ‘very easy’ or ‘easy’ to use. bBased on exact sign test of equality of paired proportions.](/cms/asset/1989fd11-8953-4418-a818-f8cc1b154cf7/iedd_a_1407755_f0003_oc.jpg)
Table 3. Responses to other questions of the User Trial Questionnaire.