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Review

Dry powder inhalation, part 1: ancient history and precursors to modern dry powder inhalers

, & ORCID Icon
Pages 1033-1044 | Received 11 Mar 2022, Accepted 09 Aug 2022, Published online: 18 Aug 2022

Figures & data

Figure 1. Ancient Egyptian technique for inhaling volatile vapors released by therapeutic herbs put on a hot stone as described in the Papyrus Ebers (1500 BCE). The stone is heated in a fire and the vapors are collected in a jar placed over the herbs having a hole in the bottom through which a reed sticks for inhaling the vapors.

Figure 1. Ancient Egyptian technique for inhaling volatile vapors released by therapeutic herbs put on a hot stone as described in the Papyrus Ebers (1500 BCE). The stone is heated in a fire and the vapors are collected in a jar placed over the herbs having a hole in the bottom through which a reed sticks for inhaling the vapors.

Figure 2. Wooden tray with condor head for the inhalation of hallucinogenic and therapeutic powdered herbs using a hollow bone as reed, San Pedro, Colombia, 700–950 CE.

Figure 2. Wooden tray with condor head for the inhalation of hallucinogenic and therapeutic powdered herbs using a hollow bone as reed, San Pedro, Colombia, 700–950 CE.

Figure 3. Inhaler Ira Warren (A: 1852 CE) and inhaler A.E. Newton (B: 1864 CE), see text for the explanations.

Figure 3. Inhaler Ira Warren (A: 1852 CE) and inhaler A.E. Newton (B: 1864 CE), see text for the explanations.

Figure 4. Carbolic smoke ball of Frederick Roe (1889 CE).

Figure 4. Carbolic smoke ball of Frederick Roe (1889 CE).

Figure 5. Aerohalor (Abbott laboratories, 1948) with sifter cartridges for isoprenaline sulfate (brand name Norisodrine) and penicillin, invented by Mack Fields.

Figure 5. Aerohalor (Abbott laboratories, 1948) with sifter cartridges for isoprenaline sulfate (brand name Norisodrine) and penicillin, invented by Mack Fields.