Navigating the crossroads: asthma, trained immunity, and infection susceptibility

Figures & data

Figure 1. The interplay between trained immunity, infection, and asthma. (this figure shows the intersection of three critical concepts: ‘trained immunity,’ ‘infection,’ and ‘asthma.’ ‘trained immunity’ is depicted as the immune system’s enhanced response to pathogens following prior exposure, potentially decreasing the susceptibility or severity of future infections. ‘Infection’ represents the entry and multiplication of pathogens in the host body, which can lead to disease. ‘Asthma’ signifies a chronic inflammatory disease of the airways. The overlap between these circles indicates that elements of trained immunity may influence the occurrence and severity of asthma and that infections can both trigger asthma exacerbations and influence the development of trained immunity).