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Case Reports

Denosumab and surgery for the treatment of Perthes’ disease in a 9-year-old boy: favorable course documented by comprehensive imaging— a case report

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Pages 354-357 | Received 01 Dec 2016, Accepted 19 Jan 2017, Published online: 14 Mar 2017

Figures & data

Figure 1. At 6 weeks. MRI (A) and contrast MRI (B). Prior to stage Ia.

Figure 1. At 6 weeks. MRI (A) and contrast MRI (B). Prior to stage Ia.

Figure 2. At 2.3 months. Start of extrusion. Subchondral fracture. Early stage Ia.

Figure 2. At 2.3 months. Start of extrusion. Subchondral fracture. Early stage Ia.

Figure 3. At 5.2 months. Contrast MRI. Cyst. Stage Ib. 2 days later, denosumab was administered.

Figure 3. At 5.2 months. Contrast MRI. Cyst. Stage Ib. 2 days later, denosumab was administered.

Figure 4. At 11.5 months. PD-weighted MRI. Beginning of loss of containment. Stage IIb.

Figure 4. At 11.5 months. PD-weighted MRI. Beginning of loss of containment. Stage IIb.

Figure 5. At 1 year. Moderate extrusion. Anterior flattening. Stage IIIa.

A proximal varus osteotomy was performed 1 month later.

Figure 5. At 1 year. Moderate extrusion. Anterior flattening. Stage IIIa.A proximal varus osteotomy was performed 1 month later.

Figure 6. Six weeks postoperatively.

Figure 6. Six weeks postoperatively.

Figure 7. At 2 years. 90% re-ossification. Stage IIIb.

Figure 7. At 2 years. 90% re-ossification. Stage IIIb.

Figure 8C. At 2 years and 8 months. An 11% increase in the maximum diameter. Almost stage IV.

Figure 8C. At 2 years and 8 months. An 11% increase in the maximum diameter. Almost stage IV.
Supplemental material

IORT_A_1298020_SUPP.PDF

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