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Articles

Blood cytokine pattern and clinical outcome in knee arthroplasty patients: comparative analysis 5 years after standard versus “hypoallergenic” surface coated prosthesis implantation

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Pages 646-651 | Received 23 Mar 2018, Accepted 24 Jul 2018, Published online: 29 Oct 2018

Figures & data

Figure 1 (left panel) Serum cytokine levels in patients with the uncoated (n = 98) and coated (n = 92) TKR (e.motion/e.motion-AS). (right panel) Serum cytokine levels in 20 patients prior to primary arthroplasty (“preoperative”) and 20 healthy individuals without implant (“controls”). The cytokines IL8, IL-6, the immunoregulatory IL-10, and the T-cell chemoattractant CXCL10 were assessed. Concentrations are given in pg/mL. b p < 0.01; c p < 0.001; standard deviation is given.

Figure 1 (left panel) Serum cytokine levels in patients with the uncoated (n = 98) and coated (n = 92) TKR (e.motion/e.motion-AS). (right panel) Serum cytokine levels in 20 patients prior to primary arthroplasty (“preoperative”) and 20 healthy individuals without implant (“controls”). The cytokines IL8, IL-6, the immunoregulatory IL-10, and the T-cell chemoattractant CXCL10 were assessed. Concentrations are given in pg/mL. b p < 0.01; c p < 0.001; standard deviation is given.

Figure 2 Relative expression levels of mRNA for IL-10 and IL-8 in peripheral blood of patients with the uncoated (n = 98) and coated (n = 92) TKR (e.motion/e.motion-AS). c p < 0.001; standard deviation is given. NS: not significant.

Figure 2 Relative expression levels of mRNA for IL-10 and IL-8 in peripheral blood of patients with the uncoated (n = 98) and coated (n = 92) TKR (e.motion/e.motion-AS). c p < 0.001; standard deviation is given. NS: not significant.

Characteristics of the 196 patients with primary TKR and of the 40 individuals without metal implant