High complication rate after extendible endoprosthetic replacement of the proximal tibia: a retrospective study of 42 consecutive children

Figures & data

Figure 1 Kaplan–Meier analysis for overall survival of 42 children who underwent proximal tibial replacement for bone tumors.

Univariate Cox regression analysis of different complication types on prosthesis survival (PS) as well as limb survival (LS) of 42 children who underwent proximal tibial replacement for bone tumors (hazards ratio with 95% confidence intervals)

Type of complication	Number of complications	Hazard ratio PS (CI)	Hazard ratio LS (CI)
I (soft tissue)	15	3 (1–9)	6 (1–37)
II (loosening)	1	0.6 (0.1–4.8)	1 (0–1000)
III (structural)	12	0.7 (0.2–2.1)	0.2 (0.1–1.6)
IV (infectious)	12	3.5 (1.1–10)	14 (2–106)
V (recurrence)	2	1.1 (0.3–5.0)	2.3 (0.3–19)

Figure 2 (left panel) Kaplan–Meier analysis for prosthesis survival of 42 children who underwent proximal tibial replacement for bone tumors. (right panel) Minimally invasive implants had a marginally superior survival as compared with non-invasive ones (p = 0.02 according to the modified Wilcoxon method and p = 0.2 according to the log-rank test, showing that minimally invasive implants have better survival only in the early follow-up period).

Figure 4 (left panel) Limb survival according to Kaplan–Meier, for 42 children who underwent proximal tibial replacement for bone tumors. (right panel) Minimally invasive implants were associated with superior limb survival (p = 0.003 according to the log-rank test and p < 0.001 according to the modified Wilcoxon method).