Analytical solutions of thermal damage in living tissues due to laser irradiation

ABSTRACT

In this article, the analytical solutions of dual-phase-lag (DPL) bioheat equation with various boundary conditions have been constructed for curative therapy of cancerous cells. The volumetric thermal source components in the model of DPL bioheat transfer, such as the metabolic heat generation and the rate of blood perfusion, are considered. The analytical solutions in the Laplace domain are obtained. The thermal injuries to the tissue are assessed by the denatured protein range, using the formulation of Arrhenius. Numerical outcomes for temperatures are graphically introduced. A parametric analysis is devoted to the identification of an appropriate procedure for selecting important design variables in order to predict more accurate to reach effective heating in hyperthermia treatment.

KEYWORDS:

• Bioheat transfer
• living tissue
• thermal damage
• dual-phase-lag model

Acknowledgments

The authors gratefully acknowledge the DSR technical and financial support.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This project was funded by the Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, under grant No (DF-174-130-1441). The authors, therefore, gratefully acknowledge the DSR technical and financial support.