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Original Articles

Functionalised iron nanoparticle–penicillin G conjugates: a novel strategy to combat the rapid emergence of β-lactamase resistance among infectious micro-organism

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Pages 718-728 | Received 30 Aug 2012, Accepted 06 Jan 2014, Published online: 05 Feb 2014

Figures & data

Figure 1 UV–visible spectrum of iron solution (…▪…), native iron nanoparticles (-•-) and functionalised iron nanoparticles (-▴-).

Figure 1 UV–visible spectrum of iron solution (…▪…), native iron nanoparticles (-•-) and functionalised iron nanoparticles (-▴-).

Figure 2 (a) AFM image of native iron nanoparticles and (b) its particle size distribution. For size distribution analysis, the diameter of approximate 100 particles were analysed.

Figure 2 (a) AFM image of native iron nanoparticles and (b) its particle size distribution. For size distribution analysis, the diameter of approximate 100 particles were analysed.

Figure 3 FTIR spectra of functionalised iron nanoparticles.

Figure 3 FTIR spectra of functionalised iron nanoparticles.

Scheme 1. Schematic illustration of penicillin G iron nanoconjugate synthesis.

Scheme 1. Schematic illustration of penicillin G iron nanoconjugate synthesis.

Figure 4 Assay for iron nanoparticle–penicillin G conjugate formation at different time scales after incubating the reaction mixture at 4 °C.

Figure 4 Assay for iron nanoparticle–penicillin G conjugate formation at different time scales after incubating the reaction mixture at 4 °C.

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