Figures & data
Figure 1. Diagram illustrating the positioning of the metabolome downstream of the genome and positioned closely to the phenome. The myriad of low molecular weight metabolites that comprise the blood metabolome is derived from endogenous processes and exogenously from the diet and activity of the gut microbiome. The environment and microbiome can also impact the genome through mutations or epigenetic effects.
Figure 2. Diagram illustrating the contribution of the ‘exogenous metabolome’ and ‘endogenous metabolome’ to the systemic and tissue metabolome.
