Hemogasometry, metabolic profile and acute-phase proteins in primiparous Holstein cows supplemented with butafosfana associated or not of cyanocobalamin

Figures & data

Table 1. Mean (±standard error of the mean) of hemogasometrics, metabolic and acute phase protein parameters of dairy cows supplemented with butafosfan associated or not with cyanocobalamin during recent postpartum period.

Parameters	Groups			Values of p
	BUT^c	BUTC^d	Control	Group	Day	Group^c day
pO2^e, mmHg	79.99 ± 12.38	75.54 ± 11.85	94.31 ± 15.47	.62	.47	.48
tCO2^g, mmol/L	31.05 ± 0.71	32.37 ± 0.68	31.44 ± 0.89	.40	<.01	.02
Bicarbonate, mmol/L	29.66 ± 0.73	31.03 ± 0.70	30.00 ± 0.91	.38	<.01	.03
Base excess, mmol/L	5.75 ± 0.86	6.33 ± 1.34	4.00 ± 1.50	.49	.01	.21
sO2^h, %	85.55 ± 2.98	85.03 ± 2.86	90.00 ± 3.73	.54	.71	.30
Haematocrit, %	26.75 ± 0.50	27.06 ± 0.49	27.06 ± 0.64	.79	.50	.99
Haemoglobin, mg/dL	9.10 ± 0.16	9.42 ± 0.15	9.22 ± 0.20	.36	.56	.83
Albumin, g/dL	2.45 ± 0.06	2.57 ± 0.06	2.56 ± 0.06	.26	.03	.94
Sodium, mmol/L	140.85 ± 4.26	133.47 ± 4.07	140.13 ± 5.32	.41	.79	.49
Potassium, mmol/L	4.30 ± 0.10	4.43 ± 0.10	4.13 ± 0.13	.20	.02	.50
Total Calcium, mg/dL	9.55 ± 0.13	9.57 ± 0.13	9.59 ± 0.14	.71	.01	.57
Phophorus, mg/dL	6.11 ± 0.16	6.05 ± 0.17	6.28 ± 0.18	.63	.09	.25
BHBA^i, mg/dL	0.52 ± 0.04	0.45 ± 0.05	0.50 ± 0.50	.58	<.01	.84
NEFA^j, mmol/L	0.31 ± 0.02	0.34 ± 0.02	0.34 ± 0.20	.36	<.01	.24
Bilirubin, mmol/L	11.14 ± 0.47	11.65 ± 0.51	11.32 ± 0.53	.76	<.01	.06
Cholesterol, mg/dL	102.42 ± 3.46	111.80 ± 3.62	107.97 ± 3.78	.18	.01	.85
Haptoglobin, mmol/L	0.46 ± 0.06	0.47 ± 0.06	0.49 ± 0.06	.93	<.01	.46
Paraoxonase, U/mL	91.79 ± 3.55^a	99.27 ± 3.76^a^,^b	105.63 ± 4.04^b	.03	.08	.78

^a,bIndicate statistical difference between groups (p < .05); ^cButafosfan; ^dButafosfan + Cyanocobalamin; ^eOxygen pressure; ^fCarbon dioxide pressure; ^gTotal carbon dioxide; ^hOxygen saturation; ⁱβ-hydroxybutyrate; ^jNon-esterified fatty acids.

Table 2. Mean (±standard error of the mean) in the days of pH, Carbon Dioxide Pressure and ionised calcium of dairy cows supplemented with butafosfan associated or not with cyanocobalamin during recent postpartum period.

Parameter	Group	Days postpartum				Group mean	p values
		0	1	2	3		Group	Day	G^aD
pH	BUT^a	7.37 ± 0.02	7.43 ± 0.02	7.47 ± 0.02	7.48 ± 0.02	7.43 ± 0.01	.07	.49	.10
	BUTC^b	7.42 ± 0.02	7.43 ± 0.02	7.40 ± 0.02	7.44 + 0.02	7.42 ± 0.01
	CTL	7.55 ± 0.05	7.44 ± 0.04	7.47 ± 0.04	7.49 ± 0.04	7.49 ± 0.02
Carbon Dioxide Pressure, mmHg	BUT	45.36 ± 2.92	41.58 ± 2.92	44.98 ± 2.92	45.52 ± 2.92	44.36 ± 1.46	.01	.22	.36
	BUTC	44.38 ± 2.66	43.41 ± 2.66	51.38 ± 2.66	45.12 ± 2.92	46.07 ± 1.40
	CTL	31.90 ± 4.62	42.85 ± 3.27	41.80 ± 3.27	40.26 ± 3.27	39.13 ± 1.83
Ionised Calcium, mmol/L	BUT	1.15 ± 0.03	1.18 ± 0.03	1.19 ± 0.03	1.21 ± 0.03	1.18 ± 0.01	<.01	.71	.39
	BUTC	1.16 ± 0.03	1.10 ± 0.03	1.14 ± 0.03	1.12 ± 0.03	1.13 ± 0.01
	CTL	1.03 ± 0.04	1.12 ± 0.03	1.10 ± 0.03	1.10 ± 0.03	1.09 ± 0.02

^aButafosfan; ^bButafosfan + Cyanocobalamin.

Figure 1. Serum glucose levels of dairy cows supplemented with butafosfan associated or not with cyanocobalamin in the recent postpartum period. Butafosfan (○ - BUT), Butafosfan + Cyanocobalamin (● - BUTC) and Control (△ - CTL). *p<.05.