https://orcid.org/0000-0002-4596-0430
Figures & data
Table 1. Chemical structure, solubility and supplier reference for cinnamaldehyde and derivatives (21 compounds in total).
Table 2. Ingredient and calculated and analysed nutrient composition of basal diet for weaned piglets from d 0 to 13 post-weaning, used in the in vivo trial.
Table 3. Antimicrobial effect of cinnamaldehyde and selected derivatives in in vitro simulations of the fermentation in the pig gut (data are presented as log10 CFU/mL; n = 3),*significantly different from control, p < .05.
Figure 1. Hierarchical cluster analysis of 11 selected compounds with their antimicrobial profiles in in vitro incubations at pH 5 (a) and pH 7 (b) with Ward’s linkage method based on Bray–Curtis dissimilarities.
Table 4. Effect of cinnamaldehyde, 2-methoxycinnamaldehyde and 4-methoxycinnamaldehyde on performance of weaned piglets from d 0 to 12 post-weaning (n = 6) and ileal and faecal apparent digestibility (n = 1 on pooled samples per treatment).
Table 5. Effect of cinnamaldehyde, 2-methoxycinnamaldehyde and 4-methoxycinnamaldehyde on bacterial counts (log10, CFU/g) and metabolites (mmol/g) in digesta of piglets sampled on d 12 or 13 post-weaning (n = 6).
Table 6. Effect of cinnamaldehyde, 2-methoxycinnamaldehyde and 4-methoxycinnamaldehyde on histo-morphology of small intestine and IEL per 100 enterocytes at 3 m distal to pylorus of piglets sampled on d 12 or 13 post-weaning (n = 6)a.
Data availability statement
The data that support the findings of this study are available from the corresponding author, E.V.L., upon reasonable request.