Figures & data
TABLE 1. Clinical and laboratory information of 15 young probable sCJD cases.
FIGURE 1. Age-distribution of 14 young probable sCJD patients. The cases numbers and the percentages of each decade group are showed inside and at top of columns.
FIGURE 2. The presences of sCJD-associated clinical signs and the relevant examinations. A. Clinical signs. I: myoclonus; II: visual or cerebellar disturbance; III: pyramidal and extrapyramidal symptoms; IV: mutism. B. Clinical examinations and laboratory tests. ND: not done. The case numbers of positive, negative and ND are showed inside of columns, respectively.
FIGURE 3. The reactive pattern of CSF RT-QuiC assays. ThT fluorescent values are indicated in Y-axis and the times (h) post-reaction are in X-axis. Pos: positive control containing 100 fg PrPSc prepared from the brain homogenate of scrapie strain 263K-infected hamster. Neg: negative control containing the same amount of the brain homogenate of normal hamster as Pos. Blank: blank control without hamster brain homogenate.
FIGURE 4. Analyses of the associations of the relevant examinations with the interval from onset to examinations (A) and the onset ages (B). P values of t tests between positive and negative groups are indicated above.
