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Short Communication

THERPA: A small molecule database related to prion protein regulation and prion diseases progression

ORCID Icon, ORCID Icon, , , , & show all
Pages 138-142 | Received 05 Mar 2018, Accepted 30 Mar 2018, Published online: 04 May 2018

Figures & data

Figure 1. Example pie chart of materials used in experiments described in the curated public articles. (A) All materials organized in this study were visualized. (B) Sub-pie chart of materials originated from mice. Click “Back to Materials” on the upper right panel of image to return to the original pie chart.

Figure 1. Example pie chart of materials used in experiments described in the curated public articles. (A) All materials organized in this study were visualized. (B) Sub-pie chart of materials originated from mice. Click “Back to Materials” on the upper right panel of image to return to the original pie chart.

Figure 2. A tree map. Each branch of the tree is given as a rectangle, tiled with smaller rectangles representing sub-branches. Each branch indicates a relationship of small molecules to PrP and/or prion diseases progression. The first sub-branch provides small molecules included in each branch. The second sub-branch provides the PMID describing the role of each small molecule. (A) Two hundred eighty-three relationships between small molecules and PrP and/or prion diseases are shown. (B) Sub-tree map structure of PrPSc downregulation is shown.

Figure 2. A tree map. Each branch of the tree is given as a rectangle, tiled with smaller rectangles representing sub-branches. Each branch indicates a relationship of small molecules to PrP and/or prion diseases progression. The first sub-branch provides small molecules included in each branch. The second sub-branch provides the PMID describing the role of each small molecule. (A) Two hundred eighty-three relationships between small molecules and PrP and/or prion diseases are shown. (B) Sub-tree map structure of PrPSc downregulation is shown.

Figure 3. Process of searching small molecules related to PrP and/or prion diseases progression.

Figure 3. Process of searching small molecules related to PrP and/or prion diseases progression.
Supplemental material

Supplementary_Table_1.xlsx

Download MS Excel (50.3 KB)

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