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Prion Volume 15, 2021 - Issue 1
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Review

The role of microglia in prion diseases and possible therapeutic targets: a literature review

Ananda Sampaio Lamenha Falcão de Meloa Faculdade de Medicina, Universidade Federal de Alagoas, Alagoas, AL, BrazilView further author information
,
Juliana Louise Dias Limaa Faculdade de Medicina, Universidade Federal de Alagoas, Alagoas, AL, BrazilView further author information
,
Maria Carolina Silva Maltaa Faculdade de Medicina, Universidade Federal de Alagoas, Alagoas, AL, BrazilView further author information
,
Natália França Marroquima Faculdade de Medicina, Universidade Federal de Alagoas, Alagoas, AL, BrazilView further author information
,
Álvaro Rivelli Moreirab Department of Neurology, Centro Universitário Governador Ozanam Coelho, UniFacog, Ubá, MG, BrazilView further author information
,
Isabelle de Almeida Ladeiab Department of Neurology, Centro Universitário Governador Ozanam Coelho, UniFacog, Ubá, MG, BrazilView further author information
,
Fabrizio dos Santos Cardosoc Núcleo de Pesquisas Tecnológicas, Universidade De Mogi Das Cruzes, Mogi das Cruzes, SP, Brazil;d Department of Psychology and Institute for Neuroscience, University of Texas (Ut), Austin, TX, USAView further author information
,
Daniel Buzaglo Gonçalvese Universidade Federal do Amazonas, Ubá, AM, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3243-970XView further author information
ORCID Icon,
Bruna Guimarães Dutrae Universidade Federal do Amazonas, Ubá, AM, BrazilView further author information
&
Júlio César Claudino dos Santosf Laboratório de Neurociências, Departamento De Neurologia E Neurocirurgia, Universidade Federal de São Paulo, São Paulo, Sp, BrazilView further author information
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Pages 191-206 | Received 26 Sep 2021, Accepted 01 Oct 2021, Published online: 09 Nov 2021

Figures & data

Figure 1. The homoeostatic microglia turning into an ameboid shape after pro-inflammatory stimulation

Figure 1. The homoeostatic microglia turning into an ameboid shape after pro-inflammatory stimulation

Table 1. Pro and anti-inflammatoy microglial targets in CDJ

Figure 2. Main immunological features and possible therapeutic targets [Citation61]

Figure 2. Main immunological features and possible therapeutic targets [Citation61]

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