2,783
Views
24
CrossRef citations to date
0
Altmetric
Review

Current drug design to target the Semaphorin/Neuropilin/Plexin complexes

, , &
Pages 700-708 | Received 15 Jul 2016, Accepted 14 Nov 2016, Published online: 01 Dec 2016

Figures & data

Figure 1. Using semaphorins as therapeutic agents. This cartoon is illustrating the major pathological conditions in which semaphorins have been shown to produce a potential therapeutic effect. The delivery mode is mentioned for each experimental in vivo models. AV, Adenovirus; AAV, Adeno-associated virus; LV, Lentivirus.

Figure 1. Using semaphorins as therapeutic agents. This cartoon is illustrating the major pathological conditions in which semaphorins have been shown to produce a potential therapeutic effect. The delivery mode is mentioned for each experimental in vivo models. AV, Adenovirus; AAV, Adeno-associated virus; LV, Lentivirus.

Figure 2. Using SNP as therapeutic targets. This schematic representation of SNP is integrating the different types of drugs targeting the extracellular or membrane domains. TMD, Trans Membrane Domain; Ab, Antibody.

Figure 2. Using SNP as therapeutic targets. This schematic representation of SNP is integrating the different types of drugs targeting the extracellular or membrane domains. TMD, Trans Membrane Domain; Ab, Antibody.