Figures & data
Figure 4. Metabolic stress changes neuronal and astrocyte [Na+]i baseline in 0BIC. Histograms showing mean values § SEM of changes of the [Na+]i baseline (ΔNa+ baseline) in neurons (left) and astrocytes (right) after perfusion of slices with magnesium-free saline containing 10 μM bicuculline (“0BIC”) for 15–20 minutes (“phase 1”) and for 90–95 minutes (“phase 3”) as compared [Na+]i in the presence of 20 mM glucose. # indicates significant differences as compared to phase 1. #/* P < 0.05, ##/** P < 0.01, ###/*** P < 0.001. 0BIC: 0 mM Mg2+ and 10 μM bicuculline; 0BIC/NaFAc: 0BIC and 1 mM NaFAc; 0BIC/lac: 0BIC and 10 mM lactate; 0BIC/NaFAc/lac: 0BIC, 1 mM NaFAC and 10 mM lactate.
![Figure 4. Metabolic stress changes neuronal and astrocyte [Na+]i baseline in 0BIC. Histograms showing mean values § SEM of changes of the [Na+]i baseline (ΔNa+ baseline) in neurons (left) and astrocytes (right) after perfusion of slices with magnesium-free saline containing 10 μM bicuculline (“0BIC”) for 15–20 minutes (“phase 1”) and for 90–95 minutes (“phase 3”) as compared [Na+]i in the presence of 20 mM glucose. # indicates significant differences as compared to phase 1. #/* P < 0.05, ##/** P < 0.01, ###/*** P < 0.001. 0BIC: 0 mM Mg2+ and 10 μM bicuculline; 0BIC/NaFAc: 0BIC and 1 mM NaFAc; 0BIC/lac: 0BIC and 10 mM lactate; 0BIC/NaFAc/lac: 0BIC, 1 mM NaFAC and 10 mM lactate.](/cms/asset/9567c7f2-c10c-45b7-ad67-359c492c8d25/kchl_a_1089118_f0001_c.gif)