Worldwide cutaneous malignant melanoma incidences analyzed by sex, age, and skin type over time (1955–2007): Is HPV infection of androgenic hair follicular melanocytes a risk factor for developing melanoma exclusively in people of European-ancestry?

Figures & data

Figure 1. Age-standardized CMM cases per 100,000 people by year for males and females with Fitzpatrick skin type I–III.

Figure 2. Age-standardized CMM cases per 100,000 people by year for males and females with Fitzpatrick skin type III–IV.

Figure 3. Age-standardized CMM cases per 100,000 people by year for males and females with Fitzpatrick skin type III–IV and IV–V.

Figure 4. Age-standardized CMM cases per 100,000 people by year for males and females with Fitzpatrick skin type V–VI.

Figure 5. Vertical y-axis is the estimated log(CMM) at 2010 for either Australian (•) or South American (▪) males and the horizontal x-axis has the 5 age groups in increasing order, i.e., age group 1 is the youngest 0–14 y. and age group 5 is the oldest, 70–85+.

Table 1. Statistical analysis of CMM over time (1955–2007) for US males and females. Significance of regression for log(CMM incidence) versus time.

Age Group	Male R^2	Female R^2	Male p values	Female p values
0–14	0.01	0.02	0.78	0.73
15–29	0.77	0.93	1.0 × 10^−3	7.6 × 10^−6
30–49	0.68	0.94	3.0 × 10^−3	3.9 × 10^−6
50–69	0.98	0.99	4.1 × 10^−8	2.9 × 10^−9
70–85+	0.94	0.98	2.0 × 10^−6	4.1 × 10^−8