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Food Additives & Contaminants: Part B
Surveillance
Volume 6, 2013 - Issue 3
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Original Articles

Antibiotics in South Indian coastal sea and farmed prawns (Penaeus monodon)

Venkatesh Palaniyappan Department of Pharmaceutical Analysis, Sir C R Reddy college of Pharmaceutical Sciences, Eluru, Andhra Pradesh, IndiaCorrespondence[email protected]
,
Arun Kumar Nagalingam Department of Pharmaceutics, KMCH college of Pharmacy, Coimbatore, Tamil Nadu, India
,
Hari Prasad Ranganathan Department of Pharmaceutical Analysis, PSG college of Pharmacy, Coimbatore, Tamil Nadu, India
,
Krishnamoorthy Bharathi Kandhikuppam Department of Pharmaceutical Analysis, Sir C R Reddy college of Pharmaceutical Sciences, Eluru, Andhra Pradesh, India
,
Hari Prasath Kothandam Department of Pharmaceutical Analysis, Sir C R Reddy college of Pharmaceutical Sciences, Eluru, Andhra Pradesh, India
&
Soumya Vasu Department of Pharmaceutical Analysis, Sir C R Reddy college of Pharmaceutical Sciences, Eluru, Andhra Pradesh, India
Pages 196-199 | Received 16 Oct 2012, Accepted 16 Mar 2013, Published online: 30 Apr 2013
 
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Abstract

Sulphonamides and chloramphenicol antibiotics were analysed by using liquid chromatography–tandem mass spectrometry (LC-MS/MS) in sea and farmed prawn (Penaeus monodon) samples obtained from the coastal region of southern India during 2011–2012. Average recoveries were 77–99% and precision was between 1% and 8%. The results revealed that in sea prawn samples neither of the two antibiotics was detected, but in farmed samples from coastal Andhra Pradesh some sulphonamides were detected in a concentration range greater than the maximum residual limit as set by Council Directive 2377/90 EC.

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