Figures & data
Figure 1. An altered testicular environment with factors such as thermal and oxidative stress, hypoxia and toxic metabolite accumulation can lead to reduced testicular function and cause alterations in the sperm DNA, like telomere shortening and DNA methylation changes. Alterations in DNA are related to loss of genomic stability, which can directly affect seminal quality, fertilization, and correct embryonic development.
Table 1. Comparative analysis of quantitative variables measured in the varicocele and control groups.
Figure 2. Variables analyzed in the varicocele and control groups. (A) DNA fragmentation index; (B) Telomere content (T/S ratio); (C) Percentage of global DNA Methylation (p > 0.05) .
Table 2. Comparative analysis of quantitative variables among varicocele patients according to varicocele grades 2 and 3 (G2 and G3).
Table 3. Spearman’s correlation matrix between the variables evaluated in the spermogram and SDF, GDM and telomere length in the group with varicocele.
