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Research Communication

Versican expression level in cumulus cells is associated with human oocyte developmental competence

ORCID Icon, , , , & ORCID Icon
Pages 176-184 | Received 25 Oct 2019, Accepted 19 Jan 2020, Published online: 06 Mar 2020

Figures & data

Figure 1. The relationship between PFKP, PKM2 and VCAN gene expression levels in cumulus cells and the corresponding oocyte development potential. Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Wilcoxon rank sum test. *P < 0.05. **P < 0.01.

Figure 1. The relationship between PFKP, PKM2 and VCAN gene expression levels in cumulus cells and the corresponding oocyte development potential. Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Wilcoxon rank sum test. *P < 0.05. **P < 0.01.

Figure 2. Effect of patient age on the gene expression in the cumulus cells. Age ≥ 35 (n = 103); age < 35 (n = 253). Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Wilcoxon rank sum test. *P < 0.05. **P < 0.01.

Figure 2. Effect of patient age on the gene expression in the cumulus cells. Age ≥ 35 (n = 103); age < 35 (n = 253). Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Wilcoxon rank sum test. *P < 0.05. **P < 0.01.

Figure 3. Effect of BMI of patients on the gene expression of the cumulus cells. Underweight (n = 45); normal weight (n = 279); overweight (n = 32). Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Kruskal–Wallis test. *P < 0.05. **P < 0.01.

Figure 3. Effect of BMI of patients on the gene expression of the cumulus cells. Underweight (n = 45); normal weight (n = 279); overweight (n = 32). Data were present as the median values (MD) and the interquartile range (IQR) and analyzed using the Kruskal–Wallis test. *P < 0.05. **P < 0.01.

Table 1. The relationship between the gene expression levels in cumulus cells and the embryo development outcomes.

Table 2. Oligonucleotide primers used for RT-PCR assays.

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