Proteomic analysis of acidocalcisomes of Trypanosoma brucei uncovers their role in phosphate metabolism, cation homeostasis, and calcium signaling

Figures & data

Figure 1. Flow chart shows steps for characterizing acidocalcisome proteome of Trypanosoma brucei. An integrated approach for functional analyses of the newly identified acidocalcisome proteins is proposed.

Figure 2. Schematic representation of the acidocalcisome of Trypanopsma brucei modified from ref. ¹¹. The newly identified acidocalcisome proteins are marked in blue while other previously identified components are shown in black.

Huang G, Ulrich PN, Storey M, Johnson D, Tischer J, Tovar JA, Moreno SN, Orlando R, Docampo R. Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells. PLoS Pathog 2014; 10:e1004555; PMID:25503798; http://dx.doi.org/10.1371/journal.ppat.1004555

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