1,636
Views
8
CrossRef citations to date
0
Altmetric
Mini-Review

How to be in a good shape? The influence of clone morphology on cell competition

&
Article: e1102806 | Received 21 Sep 2015, Accepted 28 Sep 2015, Published online: 10 Feb 2016

Figures & data

Figure 1. Compartment boundaries and cell sorting. (A) Schematic of the anterio-posterior compartment boundary in the Drosophila wing imaginal disc, which restricts the surface of contact between anterior cells (purple) and posterior cells (blue). (B) Embryonic cells from different lineages are mixed. Cell-cell adhesion reconstructs upon addition of calcium, leading to spontaneous sorting of the cell according to their lineage.

Figure 1. Compartment boundaries and cell sorting. (A) Schematic of the anterio-posterior compartment boundary in the Drosophila wing imaginal disc, which restricts the surface of contact between anterior cells (purple) and posterior cells (blue). (B) Embryonic cells from different lineages are mixed. Cell-cell adhesion reconstructs upon addition of calcium, leading to spontaneous sorting of the cell according to their lineage.

Figure 2. The influence of clone shape on cell selection. Different scenarios of cell competition (winner cells in purple, loser cells in green) with high levels of winner-loser mixing, normal levels of mixing and cell sorting (low mixing of loser and winner cells) and the expected location of dying losers (red) based on the contact dependent death induction.

Figure 2. The influence of clone shape on cell selection. Different scenarios of cell competition (winner cells in purple, loser cells in green) with high levels of winner-loser mixing, normal levels of mixing and cell sorting (low mixing of loser and winner cells) and the expected location of dying losers (red) based on the contact dependent death induction.