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Addendum

Antibiotic perturbation of the preterm infant gut microbiome and resistome

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Pages 443-449 | Received 18 May 2016, Accepted 25 Jul 2016, Published online: 18 Aug 2016

Figures & data

Figure 1. Antibiotics are the most prescribed medications in the neonatal intensive care unit. Data adapted from Clark et al. Pediatrics 2006. Citation23 Frequency defined as the number of times a unique medication name was reported in the medications table in 220 NICUs in the United States and Puerto Rico between January 1996 and April 2005.

Figure 1. Antibiotics are the most prescribed medications in the neonatal intensive care unit. Data adapted from Clark et al. Pediatrics 2006. Citation23 Frequency defined as the number of times a unique medication name was reported in the medications table in 220 NICUs in the United States and Puerto Rico between January 1996 and April 2005.

Figure 2. Antibiotic treatment significantly alters preterm infant gut microbiota development. Preterm infant gut microbiota species richness (top) and composition (bottom) for the 3 individuals with samples analyzed directly before and after depicted antibiotic treatments for (A) meropenem, (B) vancomycin and meropenem, and (C) ticarcillin-clavulanate. Red bars (left) represent species richness for example individual. Black bars (right) represent average species richness for age matched preterm infants with no antibiotic treatment. Error bars depict one standard deviation.

Figure 2. Antibiotic treatment significantly alters preterm infant gut microbiota development. Preterm infant gut microbiota species richness (top) and composition (bottom) for the 3 individuals with samples analyzed directly before and after depicted antibiotic treatments for (A) meropenem, (B) vancomycin and meropenem, and (C) ticarcillin-clavulanate. Red bars (left) represent species richness for example individual. Black bars (right) represent average species richness for age matched preterm infants with no antibiotic treatment. Error bars depict one standard deviation.

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