Figures & data
Figure 1. Effect of human adipose-derived stem cells (ADSCs) on the abdominal leak point pressure after induction of stress urinary incontinence (SUI). Upper panel: photomicrographs of the abdominal leak point pressure. Lower panel: the mean±SEM of the abdominal leak point pressure in sham-operation (A), SUI-induction (B) and SUI-induction followed by human ADSC injection (C) groups. * represents P<0.05 compared with the sham-operation group and # represents P<0.05 compared with the SUI-induction group.
Figure 2. Expression of α-smooth muscle actin in human adipose-derived stem cells (ADSCs) at 8 weeks after transplantation. Representative fluorescent staining for α-smooth muscle actin (A, green), human ADSCs stained with DiI (B, red) and superimposed images are shown here (C). Original magnification:×100.
Figure 3. Effect of human adipose-derived stem cells (ADSCs) on c-Fos expression in the pontine micturition center (PMC). Upper panels: representative photomicrographs of c-Fos-positive cells in the PMC. The sections were stained for c-Fos-like immunoreactivity (brown) as described in Materials and methods. The scale bar represents 100 µm. Lower panel: the mean number±SEM of c-Fos immunoreactivity in sham-operation (A), SUI-induction (B) and SUI-induction followed by human ADSC injection (C) groups. *represents P<0.05 compared with the sham-operation group and #represents P<0.05 compared with the SUI-induction group.
Figure 4. Effect of human adipose-derived stem cells (ADSCs) on c-Fos expression in the ventrolateral periaqueductal gray (vlPAG). Upper panels: representative photomicrographs of c-Fos-positive cells in the vlPAG. The sections were stained for c-Fos-like immunoreactivity (brown) as described in Materials and methods. The scale bar represents 100 µm. Lower panel: the mean number±SEM of c-Fos immunoreactivity in sham-operation (A), SUI-induction (B) and SUI-induction followed by human ADSC injection (C) groups. *represents P<0.05 compared with the sham-operation group and #represents P<0.05 compared with the SUI-induction group.
