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Molecular & Cellular Biology

Genome-wide transcriptional response of MPP+-treated human neuroblastoma SH-SY5Y cells to apomorphine

Pages 140-151 | Received 28 Mar 2016, Accepted 16 May 2016, Published online: 20 Jun 2016

Figures & data

Table 1. Fold changes for 18 common DEGs between MPP+-treated SH-SY5Y cells with and without APO. DEGs of SH-SY5Y cells treated with MPP+ alone were obtained from the study of Choi et al. (Citation2014).

Table 2. Enriched GO terms in DEGs obtained from MPP+-treated SH-SY5Y cells with APO. GO terms are ranked by adjusted p-value and the cut-off for the adjusted p-value was .01.

Table 3. Enriched KEGG pathways in DEGs of MPP+-treated SH-SY5Y cells, with and without APO. GO terms are ranked by adjusted p-value and the cut-off for the adjusted p-value was .05.

Figure 2. DEGs in the HIF-1 signaling pathway for MPP+-treated SH-SY5Y cells with APO. Scale bar at the top left represents the log2 fold change.

Figure 2. DEGs in the HIF-1 signaling pathway for MPP+-treated SH-SY5Y cells with APO. Scale bar at the top left represents the log2 fold change.

Figure 3. P53 signaling pathway for MPP+-treated SH-SY5Y cells with APO. Scale bar at the top left represents the log2 fold change.

Figure 3. P53 signaling pathway for MPP+-treated SH-SY5Y cells with APO. Scale bar at the top left represents the log2 fold change.

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