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Articles

Novel botulinum neurotoxin-A tibial nerve perineural injection to alleviate overactive bladder symptoms in male rats

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Pages 283-290 | Received 22 Sep 2022, Accepted 10 Oct 2022, Published online: 20 Oct 2022

Figures & data

Figure 1. Experimental set-up involving development of cyclophosphamide-induced model, followed by BoNT-A injection and cystometry analysis.

Figure 1. Experimental set-up involving development of cyclophosphamide-induced model, followed by BoNT-A injection and cystometry analysis.

Figure 2. Effects of BoNT-A administration to the tibial nerve perineural space on bladder function through cystometry. Contraction pressure, contraction time, and inter-contraction interval amongst the three experimental groups: A: Control group; B: OAB group; C: Treatment group. *P < .05 compared to the control group. #P < .05 compared to the OAB-induced group.

Figure 2. Effects of BoNT-A administration to the tibial nerve perineural space on bladder function through cystometry. Contraction pressure, contraction time, and inter-contraction interval amongst the three experimental groups: A: Control group; B: OAB group; C: Treatment group. *P < .05 compared to the control group. #P < .05 compared to the OAB-induced group.

Figure 3. Schematic comparison between the treatment mechanism of the current study and that suggested by DTTS and conventional PTNS.

Figure 3. Schematic comparison between the treatment mechanism of the current study and that suggested by DTTS and conventional PTNS.