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Journal of Oral Microbiology Volume 13, 2021 - Issue 1
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Review Article

Potential implications of SARS-CoV-2 oral infection in the host microbiota

Zhenting Xianga Biofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA;b State Key Laboratory of Oral Disease & Human Saliva Laboratory & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
,
Hyun Kooa Biofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA;c Center for Innovation & Precision Dentistry, School of Dental Medicine, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA
,
Qianming Chend Stomatology Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, ZhejiangChina
,
Xuedong Zhoub State Key Laboratory of Oral Disease & Human Saliva Laboratory & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China
,
Yuan Liua Biofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USACorrespondence[email protected]
&
Aurea Simon-Soroa Biofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA;e Department of Stomatology, School of Dentistry, University of Seville, Seville, SpainCorrespondence[email protected]
Article: 1853451 | Received 06 Oct 2020, Accepted 17 Nov 2020, Published online: 29 Nov 2020

Figures & data

Figure 1. A conceptual framework of the impact of SARS-CoV-2 oral infection on the local and distant microbiomes across the ‘oral-tract axes’. The left panel illustrates the potential reservoirs of SARS-CoV-2 during the infection of the oral cavity. The right panel highlights current knowledge and potential interactions of the virus across the oral/gastrointestinal and respiratory tracts, which remain largely unexplored

Figure 1. A conceptual framework of the impact of SARS-CoV-2 oral infection on the local and distant microbiomes across the ‘oral-tract axes’. The left panel illustrates the potential reservoirs of SARS-CoV-2 during the infection of the oral cavity. The right panel highlights current knowledge and potential interactions of the virus across the oral/gastrointestinal and respiratory tracts, which remain largely unexplored

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