Comparison of inflammatory response and synovial metaplasia in immediate breast reconstruction with a synthetic and a biological mesh: a randomized controlled clinical trial

Figures & data

Figure 1. Examples of biopsies. Masson trichrome staining, original magnification 40x (a,d); 100x (b,e); α-smooth muscle actin, original magnification 40x (c,f). (A–C) illustrates a type A reaction and d-f a type B reaction. Small arrow: synovial metaplasia. Arrow head: mesh fibers. Asterix: collagen fibers. Thick arrow: actine positive myofibroblasts.

Table 1. Morphological evaluation of the biopsies.

	Biological mesh	Synthetic mesh
Type A (n = 10)	0 (0%)	10 (67%)
Type B (n = 13)	11 (73%)	2 (13%)
Type C (n = 5)	2 (14%)	3 (20%)
Only hyaline material (n = 2)	2 (14%)	0
Total (n = 29)	15	15

The different morphological types are described in the text.

Table 2. Result of actin immunohistostaining.

Myofibroblasts Semiquantative score (0–3)
	Biological (n = 14)	Synthetic (n = 14)
1	3	3
2	3	8
3	4	2
4	4	1

Two of the biological biopsies were not possible to evaluate immunohistochemically as there was only hyaline material.