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Basic Research Article

Exposure-based treatments for childhood abuse-related post-traumatic stress disorder in adults: a health-economic evaluation

Tratamientos basados en la exposición para el trastorno de estrés postraumático relacionado con el abuso infantil en adultos: una evaluación económica de la salud

成人童年期虐待相关创伤后应激障碍的暴露治疗:一项健康经济评估

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Article: 2171752 | Received 31 Aug 2022, Accepted 17 Dec 2022, Published online: 14 Feb 2023

Figures & data

Table 1. Baseline characteristics of the study sample (N = 149).

Table 2. Average volumes, costs, and quality-adjusted life-years (QALYs) per patient, by condition.

Figure 1. Average utility through the year, according to (A) the 5-level EuroQol 5 Dimensions (EQ-5D-5L) and (B) the visual analogue scale (VAS). T0 = Baseline; T1 = after 4 weeks (4 sessions of STAIR + PE or PE or 12 sessions of i-PE); T2 = after 8 weeks (8 sessions of STAIR + PE or PE or 13 sessions of i-PE); T3 = after 16 weeks (i.e. post-treatment); T4 = 6 month follow-up (26 weeks); T5 = 12 month follow-up (52 weeks). PE, prolonged exposure; i-PE, intensified prolonged exposure; STAIR, Skills Training in Affective and Interpersonal Regulation.

Figure 1. Average utility through the year, according to (A) the 5-level EuroQol 5 Dimensions (EQ-5D-5L) and (B) the visual analogue scale (VAS). T0 = Baseline; T1 = after 4 weeks (4 sessions of STAIR + PE or PE or 12 sessions of i-PE); T2 = after 8 weeks (8 sessions of STAIR + PE or PE or 13 sessions of i-PE); T3 = after 16 weeks (i.e. post-treatment); T4 = 6 month follow-up (26 weeks); T5 = 12 month follow-up (52 weeks). PE, prolonged exposure; i-PE, intensified prolonged exposure; STAIR, Skills Training in Affective and Interpersonal Regulation.

Figure 2. Cost-effectiveness acceptability curves, i.e. the probability that each of the conditions is economically preferred over the other two conditions, depending on the willingness to pay per quality-adjusted life-year (QALY). (A) Base-case analysis, based on societal costs and QALYs estimated from the 5-level EuroQol 5 Dimensions (EQ-5D-5L); (B) sensitivity analysis based on intervention costs (instead of societal costs) and QALYs estimated from the EQ-5D-5L; (C) sensitivity analysis based on societal costs and QALYs estimated from the visual analogue scale (instead of the EQ-5D-5L).

Figure 2. Cost-effectiveness acceptability curves, i.e. the probability that each of the conditions is economically preferred over the other two conditions, depending on the willingness to pay per quality-adjusted life-year (QALY). (A) Base-case analysis, based on societal costs and QALYs estimated from the 5-level EuroQol 5 Dimensions (EQ-5D-5L); (B) sensitivity analysis based on intervention costs (instead of societal costs) and QALYs estimated from the EQ-5D-5L; (C) sensitivity analysis based on societal costs and QALYs estimated from the visual analogue scale (instead of the EQ-5D-5L).

Data availability

Proposals for the use of data and requests for access should be directed to [email protected].