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Clinical Research Article

Post-traumatic stress disorder and drug use disorder: examination of aetiological models in a Swedish population-based cohort

Trastorno de estrés postraumático y trastorno por uso de sustancias: examen de modelos etiológicos en una cohorte de población sueca

创伤后应激障碍和药物使用障碍:瑞典人群群体的病因模型考查

ORCID Icon, , , &
Article: 2258312 | Received 14 Dec 2022, Accepted 24 Jul 2023, Published online: 06 Oct 2023

Figures & data

Table 1. Frequency of key variables stratified by sex and drug use disorder (DUD) and post-traumatic stress disorder (PTSD) status.

Table 2. Adjusted hazard ratios for Cox models testing the self-medication and susceptibility models adjusted for covariates.

Table 3. Descriptive table for the cross-lagged panel model.

Figure 1. (a) Cross-lagged panel model of registrations of post-traumatic stress disorder (PTSD) and drug use disorder (DUD), starting at the age of 15 years, in 5 year epochs between the ages of 35 and 50 years. Five types of paths are shown: the ‘a’ paths refer to the stability paths for PTSD, the ‘b’ paths refer to the stability paths for DUD, the ‘c’ paths denote the within-time correlations between PTSD and DUD, the ‘d’ paths represent the self-medication pathway, and the ‘e’ paths denote the susceptibility pathway. (b) Standardized path coefficient results from the cross-lagged panel model, by sex.

Figure 1. (a) Cross-lagged panel model of registrations of post-traumatic stress disorder (PTSD) and drug use disorder (DUD), starting at the age of 15 years, in 5 year epochs between the ages of 35 and 50 years. Five types of paths are shown: the ‘a’ paths refer to the stability paths for PTSD, the ‘b’ paths refer to the stability paths for DUD, the ‘c’ paths denote the within-time correlations between PTSD and DUD, the ‘d’ paths represent the self-medication pathway, and the ‘e’ paths denote the susceptibility pathway. (b) Standardized path coefficient results from the cross-lagged panel model, by sex.
Supplemental material

Supplemental Material

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Data availability

The data are not publicly available owing to restrictions with regard to the nationwide Swedish registers.