Unresolved–disorganized attachment adjusted for a general psychopathology factor associated with atypical amygdala resting-state functional connectivity

Figures & data

Table 1. General psychopathology scores, age, total IQ, and PDS scores for the Ud and non-Ud groups.

	Ud (N = 16)		Non-Ud (N = 58)
	M	SD	M	SD
GPF	0.38	0.97	−0.11	0.99
Age	15.56	1.63	15.38	1.69
Total IQ	99.38	8.40	104.36	8.89
PDS scores	4.19	0.98	4.22	0.73

M, mean; SD, standard deviation; GPF, general psychopathology factor; IQ, intelligence quotient; PDS, Pubertal Development Scale; Ud, unresolved–disorganized attachment.

Table 2. Cluster size, lowest p-value, and coordinates of the significant clusters resulting from the analyses with the amygdala as seed region.

Contrast	Region	Voxels	p	x	y	z
Unresolved loss and trauma +	Left superior parietal lobule	80	.02	−20	−56	48
	Left superior parietal lobule	25	.04	−24	−52	34
	Left lateral occipital cortex	8	.05	−28	−66	34
Unresolved loss and trauma^a –	Right medial frontal cortex	189	.02	12	50	−16

^aResults from the region of interest (ROI) analysis with the medial frontal cortex as a priori defined ROI.

Figure 1. (a) Significant positive association between unresolved loss and trauma and left amygdala–lateral occipital cortex connectivity, resulting from the whole-brain analysis, Threshold Free Cluster Enhancement (TFCE) family-wise corrected, p < .05. (b) Significant negative association between unresolved loss and trauma and left amygdala–medial frontal cortex connectivity, resulting from the region of interest (ROI) analysis, TFCE family-wise corrected, p < .05. The right side of the brain corresponds to the left hemisphere and vice versa.