The sense of self in the aftermath of trauma: lessons from the default mode network in posttraumatic stress disorder

Figures & data

Figure 1. Images show the functional connectivity of the DMN in healthy controls (left) and in participants with PTSD (right) under different conditions. Top and bottom images depict within-group patterns in functional connectivity during rest and during trauma-related stimulus processing, respectively. Whereas resting-state functional connectivity is depicted in relation to the time series of the posterior cingulate cortex (PCC), trauma-related functional connectivity is depicted in relation to the time series of the periaqueductal grey (PAG). Figure 1 is an adaptation from two previous findings, where resting-state and threat-related functional connectivity are related to results by Bluhm et al. (2009) and Terpou et al. (2019a), respectively

Bluhm, R. L. , Williamson, P. C. , Osuch, E. A. , Frewen, P. A. , Stevens, T. K. , Boksman, K. , & Lanius, R. A. (2009). Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma. Journal of Psychiatry and Neuroscience , 34(3), 187–194.

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Terpou, B. A. , Densmore, M. , Théberge, J. , Thome, J. , Frewen, P. , McKinnon, M. C. , & Lanius, R. A. (2019a). The threatful self: Midbrain functional connectivity to cortical midline and parietal regions during subliminal trauma-related processing in PTSD. Chronic Stress , 3, 247054701987136.

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