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Editorial

A geroscience mouse model for Alzheimer’s disease

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Figures & data

Figure 1. The relationship between biological aging and age-related diseases can be studied as a multidisciplinary field known as geroscience. Aging mice can be used as models of human aging to investigate the effect of aging on age-related diseases.

Figure 1. The relationship between biological aging and age-related diseases can be studied as a multidisciplinary field known as geroscience. Aging mice can be used as models of human aging to investigate the effect of aging on age-related diseases.

Figure 2. Multiple brain regions of the aging mouse can be targeted with Aβ42 and P301Ltau. This allows induction of pathology at a disease-relevant age and restricts pathology to injected brain regions based on their relevance to AD.

Figure 2. Multiple brain regions of the aging mouse can be targeted with Aβ42 and P301Ltau. This allows induction of pathology at a disease-relevant age and restricts pathology to injected brain regions based on their relevance to AD.