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Original Research Article

Health-related quality of life in health states corresponding to different stages of perianal fistula associated with Crohn’s disease: a quantitative evaluation of patients and non-patients in Japan

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Article: 2166374 | Received 19 Jun 2022, Accepted 03 Jan 2023, Published online: 15 Jan 2023

Figures & data

Table 1. Descriptions of health states of perianal fistula associated with Crohn’s disease used in the survey.

Figure 1. Example of standard time trade-off internet survey screen.

Note: TTO, time trade-off
Figure 1. Example of standard time trade-off internet survey screen.

Figure 2. Example of lead-time time trade-off internet survey screen.

Note: TTO, time trade-off
Figure 2. Example of lead-time time trade-off internet survey screen.

Figure 3. Flow chart of participants.* Total number of Medilead Healthcare Panel registrants. When registering for the panel, a total of 419 people reported that they had visited a medical institution for Crohn’s disease in the past. ** Comprises 419 people registered as having visited a medical institution for Crohn’s disease and 13,190 people randomly selected from the remaining non-Crohn’s disease patients. *** The allocation to the patient or non-patient group was based on the results of the screening survey, not on the information given by people when they registered with the panel. QOL, quality of life; TTO, time trade-off

Figure 3. Flow chart of participants.* Total number of Medilead Healthcare Panel registrants. When registering for the panel, a total of 419 people reported that they had visited a medical institution for Crohn’s disease in the past. ** Comprises 419 people registered as having visited a medical institution for Crohn’s disease and 13,190 people randomly selected from the remaining non-Crohn’s disease patients. *** The allocation to the patient or non-patient group was based on the results of the screening survey, not on the information given by people when they registered with the panel. QOL, quality of life; TTO, time trade-off

Table 2. Background information of valid responders.

Table 3. Utility values in each health state.

Table 4. Utility values based on actual health state at the time of the survey of patients with Crohn’s disease.

Table 5. Results of linear mixed model analysis of utility values.

Supplemental material

Supplemental Material

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Data availability statement

We have not acquired an agreement from participants of this study for data to be shared publicly, so supporting data are not available.