Ergospirometry with concurrent fibre optic laryngoscopy: a randomised crossover study

Figures & data

Figure 1. Flow diagram. All patients registered to undergo a CLE during the study period were considered for inclusion, n = 154 patients. Screen failures were due to negative EILO findings,[2] self-reported activity (daily workout > 3 hours or daily cycling commute longer than 15 km),[4] and high VO₂max.[5] Thirteen patients were eligible for inclusion of whom two declined due to unrelated reasons. Eleven participants underwent all three tests, i.e. pre-test on ergometer bicycle test, continuous laryngoscopy during exercise (CLE) on ergometer bicycle and CLE on treadmill

Table 1. Participant characteristics

Part.	Sex	Age in years	Height in centimetres	Weight in kilograms	FEV1% of pred.	FVC % of pred.	Co-morbidity
1	Female	21	164	59.50	120.6	119.5	No
2	Female	18	176	71.00	100	99.6	Asthma
3	Female	43	170	82.00	124.6	139.6	No
4	Female	29	165	62.00	105.9	137.8	Asthma
5	Female	33	177	75.20	105.1	125.6	No
6	Female	19	167	80.10	124.4	124.4	Asthma
7	Female	21	165	60.50	112.1	117.2	No
8	Female	21	167	61.60	125.8	120.6	No
9	Female	43	178	103.80	142.7	164.8	No
10	Female	25	170	59.20	86.1	85.7	Asthma
11	Male	37	173	66.10	99.5	123.3	No
Total	F: 91%/M: 9%	28(9)^a	170 (5)^a	71 (14)^a	113 (16)^a	123 (21) ^a	Asthma: 36%

Part: participant.

F: female, M: male.

FEV₁: forced expiratory volume in first second percentage of predicted.

FVC: forced expiratory volume percentage of predicted.

^a Numbers are mean (standard deviation)

Table 2. Ergospirometry and CLE results

CLE, treadmill			Ergospirometry, bike				Ergospirometry with CLE, bike
	Test duration	EILO	VO2max	%Pred VO2	Test duration	RPE	VO2max	%Pred VO2	Test duration	RPE	EILO
Part.	(sec)	G/SG	(ml·kg^–1 ·min^–1)		(sec)		(ml·kg^–1·min^–1)		(sec)		G/SG
1	270	0/2	41.9	97.4	495	17	46	107	515	19	0/2
2	255	0/2	35.1	79.6	520	19	38.5	87.4	510	19	0/2
3	270	0/2	30.4	87.2	432	18	33.4	95.8	415	18	0/2
4	210	1/2	40.2	100.4	465	19	44.1	110.3	420	19	0/2
5	260	0/2	33.1	85.9	480	18	36.4	94.4	490	19	0/2
6	186	2/3	31.1	71.1	515	20	34.2	78.1	510	20	1/3
7	245	0/2	41.2	95.8	475	20	45.2	105.2	490	20	0/2
8	270	2/2	40.4	94.1	505	19	44.4	103.3	510	20	1/2
9	240	0/2	24	68.9	540	19	26.4	75.7	575	19	1/3
10	375	2/3	42.1	101.4	500	19	46.2	111.4	460	19	2/2
11	360	2/0	37.7	101.7	575	20	41.4	111.7	560	20	0/0
Tot ^a	267.4		36.1	88.9	500.2	18	39.7	98.2	495.9	19.3
	(56.2)		(5.9)	(11.9)	(38.4)	(0.9)	(6.5)	(13)	(50)	(0.6)

CLE: Continuous laryngoscopy during exercise.

Part: participant.

Sec: seconds

EILO: exercise-induced laryngeal obstruction.

G/SG: glottic/supraglottic EILO.

VO2 max: maximum oxygen uptake.

RPE scale: Borg rating of perceived exertion scale.

^a Tot: total. Numbers are mean (standard deviation).

Table 3. Ergospirometry measurements

	Without CLE	With CLE	P ^a
Maximum heart rate	191 (12)	191 (13)	0.6
Respiratory exchange ratio (RER)	1.24 (0.13)	1.17 (0.13)	0.1
Maximum watt achieved during test	194 (35.4)	203 (18.7)	0.8
Test duration in minutes	8.3 (0.6)	8.6 (1.5)	0.8
Maximal oxygen uptake in millilitres of O2 per minute	2608 (303)	2586 (308)	0.65

All values in this table are noted as mean (SD) unless otherwise stated.

a: paired t-tests

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