From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process

Respiratory and Cardiovascular Effects in COPD (KOLIN)

Anne LindbergDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, SwedenCorrespondence[email protected]
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Robert LinderDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, Sweden

https://orcid.org/0000-0003-4266-1782 View further author information

Helena BackmanDepartment of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, Umeå University, Umeå, Sweden

https://orcid.org/0000-0002-0553-8067 View further author information

Jonas Eriksson StrömDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, SwedenView further author information

Andreas FrølichDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, SwedenView further author information

Ulf NilssonDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, Sweden

https://orcid.org/0000-0002-2574-479X View further author information

Eva RönmarkDepartment of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, Umeå University, Umeå, SwedenView further author information

Viktor StrandkvistDepartment of Health Science, Division of Health and Rehabilitation, Luleå University of Technology, Luleå, Sweden

https://orcid.org/0000-0002-5948-6880 View further author information

Annelie F. BehndigDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, SwedenView further author information

Anders BlombergDepartment of Public Health and Clinical Medicine, Division of Medicine, Umeå University, Umeå, SwedenView further author information

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From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process

Respiratory and Cardiovascular Effects in COPD (KOLIN)

Table 1. Total number of subjects within the groups A–D identified in the OLIN COPD study data base at baseline in 2002–2004 and follow-up in 2010 (first recruitment phase) or 2012/2013 (second recruitment phase); characteristics at baseline in 2002–2004 for each of the groups

Table 2. The reason for non-participation in the study program among subjects classified as groups A and B, respectively

Table 3. Characteristics at the time for the examination in 2010 (first recruitment phase) respectively 2012/2013 (second recruitment phase) of the participants in groups A_{p –} D_p.

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From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process

Respiratory and Cardiovascular Effects in COPD (KOLIN)

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Table 1. Total number of subjects within the groups A–D identified in the OLIN COPD study data base at baseline in 2002–2004 and follow-up in 2010 (first recruitment phase) or 2012/2013 (second recruitment phase); characteristics at baseline in 2002–2004 for each of the groups

Table 2. The reason for non-participation in the study program among subjects classified as groups A and B, respectively

Table 3. Characteristics at the time for the examination in 2010 (first recruitment phase) respectively 2012/2013 (second recruitment phase) of the participants in groups Ap – Dp.

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Table 3. Characteristics at the time for the examination in 2010 (first recruitment phase) respectively 2012/2013 (second recruitment phase) of the participants in groups A_{p –} D_p.