Validation of the COPD Assessment Test (CAT) in patients with idiopathic pulmonary fibrosis

Figures & data

Table 1. Characteristics of the study population, 87 patients with idiopathic pulmonary fibrosis.

	N (%) or Mean (SD)
Male	54 (62 %)
Age (years)	70.1 (10.1)
Treatment
Pirfenidone	42 (48.3 %)
Nintedanib	5 (5.7 %)
None	40 (46.0 %)
FVC (litre)^1	2.88 (0.85)
FEV1 (%)^2	84.21 (19.76)
CAT	16.76 (6.83)
DLCO (%)^3	45.01 (13.16)
6 MWD (m)^4	424.6 (108.1)
Saturation before 6 MWD^4	95.23 (2.37)
Saturation after 6 MWD^4	84.39 (7.99)
GAP Index^5	1.63 (0.64)
MRC^6	2.69 (1.08)
SGRQ Symptoms^7	54.05 (21.18)
SGRQ Activity^8	57.45 (24.12)
SGRQ Impact^9	33.88 (19.57)
SGRQ Total score^10	45.09 (19.76)

¹6 values missing; ²7 values missing; ³7 values missing; ⁴31 values missing; ⁵5 values missing; ⁶32 values missing; ⁷41 values missing; ⁸40 missing; ⁹43 missing; ¹⁰46 values missing.

Figure 1. Distribution of the SGRQ total score according to the GAP index in patients with IPF

(GAP index 1 n = 37, GAP index 2 n = 38, GAP index 3 n = 7).

SGRQ – The St. George’s Respiratory Questionnaire, IPF- Idiopathic Pulmonary Fibrosis, GAP Index – Gender, age and physiology.

Figure 2. Distribution of the CAT score according to the GAP index in patients with IPF.

(GAP index 1 n = 37, GAP index 2 n = 38, GAP index 3 n = 7)

SGRQ – The St. George’s Respiratory Questionnaire, IPF- Idiopathic Pulmonary Fibrosis, GAP Index – Gender, age and physiology.

Table 2. Spearman correlations between the CAT and SGRQ scores and physiological variables in patients with IPF.

	CAT	SGRQ total score
Age	−.053	−.008
FVC	−.338**	−.339*
FVC (%)	−.425**	−.433**
FEV1	−.252*	−.127
FEV1 (%)	−.323**	−.367*
FEV1/FVC	.0162	.229
DLCO	−.346**	−.299
DLCO (%)	−.348**	−.280
6 MWD	−.582**	−.796**
MRC	.646**	. 805**
CAT		.8**
Desaturation at 6 MWD	.679**	.06

**Correlation is significant at the 0.01 level (2-tailed).

*Correlation is significant at the 0.05 level (2-tailed).

Figure 3. Correlation between the CAT and SGRQ total scores in patients with IPF.

Pearson correlation 0.8

SGRQ – The St. George’s Respiratory Questionnaire, IPF- Idiopathic Pulmonary Fibrosis, GAP Index – Gender, age and physiology.