Long-term non-invasive ventilation for stable chronic hypercapnic COPD

Figures & data

Figure 1. Flowchart of the study selection process.

Table 1. Main characteristics of included studies.

Study	Location	Study design	Population (n) (treatment/control)	Intervention (treatment/control)
Clini (2002)	Italy/France	RCT	43/47	(LTN IV+LTOT)/LTOT
McEvoy (2009)	Australia	RCT	72/72	(LTN IV+LTOT)/LTOT
Kohnlein (2014)	Germany	RCT	102/93	(LTN IV+LTOT)/LTOT
Struik (2014)	The Netherlands	RCT	101/100	(LTN IV+LTOT)/LTOT
Zhou (2017)	China	RCT	57/58	(LTN IV+LTOT)/LTOT
Murphy (2017)	Great Britain	RCT	57/59	(LTN IV+LTOT)/LTOT

Abbreviations: RCT, randomized controlled trial; LTNIV, long-term non-invasive ventilation; LTOT, long-term oxygen treatment; n, number.

Figure 2. Partial pressure of carbon dioxide forest plot.

Figure 3. Subgroups, partial pressure of carbon dioxide forest plot study or subgroup.

Figure 4. Mortality forest plot.

Figure 5. Subgroup, mortality forest plot.