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Research Article

Real-world evidence effect of budesonide+formoterol Spiromax on patients with asthma and chronic obstructive pulmonary disease in Sweden

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Article: 1660565 | Received 12 Feb 2019, Accepted 23 Aug 2019, Published online: 13 Sep 2019

Figures & data

Figure 1. Patient flow diagram. aPatients who were excluded due to adherence criteria, and who died prior to the end of the follow-up period are listed in both of the exclusion categories; bPatients who were excluded, were excluded due to lack of adherence. To be included, all patients had to be on BF Spiromax for the entire follow-up, with a minimum of two prescriptions. BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease.

Figure 1. Patient flow diagram. aPatients who were excluded due to adherence criteria, and who died prior to the end of the follow-up period are listed in both of the exclusion categories; bPatients who were excluded, were excluded due to lack of adherence. To be included, all patients had to be on BF Spiromax for the entire follow-up, with a minimum of two prescriptions. BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease.

Table 1. Patient characteristics among an eligible patient population.

Figure 2. Percentage of patients with an exacerbation before and after initiating BF Spiromax for the asthma patient group (a), the asthma/COPD patient group (b), and the COPD patient group (c). BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroid; LABA: long-acting β2-agonist.

Figure 2. Percentage of patients with an exacerbation before and after initiating BF Spiromax for the asthma patient group (a), the asthma/COPD patient group (b), and the COPD patient group (c). BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroid; LABA: long-acting β2-agonist.

Table 2. Asthma/COPD treatments before and after initiation to BF Spiromax in the total population.

Figure 3. Inpatient and specialized outpatient care before and after initiating BF Spiromax in patients with asthma (a), asthma/COPD (b), or COPD (c). BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease.

Figure 3. Inpatient and specialized outpatient care before and after initiating BF Spiromax in patients with asthma (a), asthma/COPD (b), or COPD (c). BF: budesonide+formoterol; COPD: chronic obstructive pulmonary disease.

Figure 4. Cost of medications (units of euros) and secondary care before and after initiating BF Spiromax in patients with asthma (a), Asthma and COPD (b) or COPD (c). BF, budesonide+formoterol; COPD, chronic obstructive pulmonary disease.

Figure 4. Cost of medications (units of euros) and secondary care before and after initiating BF Spiromax in patients with asthma (a), Asthma and COPD (b) or COPD (c). BF, budesonide+formoterol; COPD, chronic obstructive pulmonary disease.