Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites

Figures & data

Table 1. Well-known Drugs produced by Fusarium species through in vitro fermentation.

Medicines	Producing- fungal	Host-plant	Production yield	References
Quinine and Cinchonidine	F. incarnatum, F. oxysporum, F. solani	C. calisaya	0.8–0.9mg/L	Hidayat et al. (2015)
Camptothecin	F. solani	C. acuminata	150 μg/L	Ran et al. (2017)
		-	28.9 μg/L	Venugopalan et al. (2016)
		A. dimidiata	37–53 µg/100 g	Shweta et al. (2010)
		C. acuminata	*	Kusari et al. (2009)
	F. sacchari	N. nimmoniana	*	Gurudatt et al. (2010)
10-hydroxycamptothecin	F. solani	A. dimidiata	8.2 µg/100 g	Shweta et al. (2010)
		C. acuminata	*	Kusari et al. (2009)
9-methoxycamptothecin	F. solani	A. dimidiata	44.9 µg/100 g	Shweta et al. (2010)
		C. acuminata	*	Kusari et al. (2009)
Ginkgolide B	F. oxysporum	G. biloba	*	Cui et al. (2012)
Podophyllotoxin	F. oxysporum	J. recurva	28μg/g	Kour et al. (2008)
	F. solani	P. hexandrum	29.0μg/g	Nadeem et al. (2012)
Rohitukine	F. oxysporum	D. binectariferum	2.952 μg/g	Kumara et al. (2014)
	F. oxysporum	D. binectariferum	3.2949μg/g
	F. solani	D. binectariferum	3.5955μg/g
Taxol	F. oxysporum	R. annamalayana	172.3 μg/L	Elavarasi et al. (2012)
	F. anthrosporioides	T. cuspidata	131 μg/L	Li et al. (2008)
	F. lateritium	T. buccata	0.13 μg/L	Strobel et al. (1996)
	F. mairei	T. mairei	225.2 μg/L	Xu et al. (2006)
	F. mairei	T. chinensis var mairei	2.72 μg/L	Cheng et al. (2007)
	F. mairei	T. chinensis var mairei	286.4 μg/L	Dai and Tao (2008)
	F. mairei	T. x media	20 μg/L	Dai and Tao (2008)
	F. oxysporum	R. annamalayamna	*	Elavarasi et al. (2012)
	F. redolens	T. buccata	66.0 μg/L	Garyali et al. (2013)
	F. solani	T. chinensis	163.35 μg/L	Deng et al. (2009)
	F. solani	T. celebica	1.6 μg/L	Chakravarthi et al. (2008)
	F. mairei	T. chinensis var. mairei	25.63 mg/L	Li et al. (2009)
	F. proliferatum	T. media	240 ng/L	Xiong et al. (2013)
Vinblastine	F. oxysporum	C. roseus	76 µg/L	Kumar et al. (2013)
Vincristine			67 µg/L
Vinblastine and vincristine	F. solani	C. roseus	*	Ashuthosh et al. (2013)

Figure 1. Selected antimicrobial compounds reported from Fusarium endophytes.

Figure 1. (Continued).

Figure 2. Antitrypanosomal and antileishmanial compounds from Fusarium spp.

Figure 3. Antiviral compounds from produced by Fusarium species.

Figure 4. Anticancer compounds isolated from Fusarium species.

Figure 5. Antioxidant and antiaging compounds reported from Fusarium spp.

Figure 6. Metabolites with ability to influence the immune isolated from Fusarium spp.

Figure 7. Nematicidal compounds produced by Fusarium spp.

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