http://orcid.org/0000-0001-7410-1865
Figures & data
Figure 1. Cellular immunotherapy strategies. Cancer immune response starts with the release of tumor-associated antigens and danger signals by dying tumor cells (immunogenic cell death). Dendritic cells capture tumor-associated antigens and mature due to the detection of danger signals by pattern-recognition receptors. Upon migration to the lymph node, dendritic cells are able to trigger the effector antitumor response. Cytotoxic T lymphocytes and NK cells recognize and kill the tumor cells. Adoptive transfer of dendritic cells, T cells or NK cells are being used to boost this process.
