Figures & data
Table 1. Characteristics of the patients enrolled in this study
Figure 1. Differential gene expression analysis between peripheral T lymphocytes from patients with melanoma (c) and patients with melanoma treated with AGI-101H 6 days after vaccine administration (AV) using HG U219 microarray data
![Figure 1. Differential gene expression analysis between peripheral T lymphocytes from patients with melanoma (c) and patients with melanoma treated with AGI-101H 6 days after vaccine administration (AV) using HG U219 microarray data](/cms/asset/ae7d558a-0ce5-49e7-8e22-72c62e012af7/koni_a_1710063_f0001_oc.jpg)
Figure 2. Significantly up-regulated markers in the peripheral T cells of AGI-101H-immunized patients are mainly involved in the regulation of gene transcription
![Figure 2. Significantly up-regulated markers in the peripheral T cells of AGI-101H-immunized patients are mainly involved in the regulation of gene transcription](/cms/asset/257ffc17-c65d-4992-9577-82ba98d44daf/koni_a_1710063_f0002_oc.jpg)
Figure 3. The expression of BCL6 transcriptional repressor is significantly up-regulated in the peripheral T cells of AGI-101 immunized patients with melanoma and negatively correlates with the expression of BCL6 target genes as well as the expression of “exhaustion markers.”
![Figure 3. The expression of BCL6 transcriptional repressor is significantly up-regulated in the peripheral T cells of AGI-101 immunized patients with melanoma and negatively correlates with the expression of BCL6 target genes as well as the expression of “exhaustion markers.”](/cms/asset/1a958bc6-44bb-4f0e-a3ed-4650572bf712/koni_a_1710063_f0003_oc.jpg)
Figure 4. Gene set enrichment analysis (GSEA) revealed significant up-regulation of TNF-a (via NFkβ) and down-regulation of IL2-STAT5 signaling in the peripheral T cells from AGI-101H-vaccinated patients with melanoma
![Figure 4. Gene set enrichment analysis (GSEA) revealed significant up-regulation of TNF-a (via NFkβ) and down-regulation of IL2-STAT5 signaling in the peripheral T cells from AGI-101H-vaccinated patients with melanoma](/cms/asset/ea3a6862-d2cb-49b2-868e-6dde8c421a14/koni_a_1710063_f0004_oc.jpg)