https://orcid.org/0000-0003-2524-1815
Figures & data
Figure 1. PR and STAT2 interact without affecting STAT2 phosphorylation.
Figure 2. PR activation promotes STAT2 ubiquitination and subsequent protein degradation.
Figure 3. Interferon-induced DNA binding is maintained in the absence of STAT1.
Figure 4. ISGF3 binding is severely hindered in the absence of STAT2.
Figure 5. STAT2 is essential for efficient ISG transcription.
Figure 6. PR status in human tumors is correlated with decreased interferon gene signature.
Figure 7. PR inhibits type I interferon signaling by targeting both STAT1 and STAT2.
Supplemental material