Two models for changes of EV71 immunity in infants and young children

Figures & data

Table 1. EV71 positive rate of 420 subjects

Age (months)	Number evaluated	Number positive	Positive rate
Newborn	20	14	70%
1	20	11	55%
2	20	5	25%
3	30	1	3%
4	30	3	10%
5	30	0	0%
6	30	1	3%
7	20	2	10%
8	20	1	5%
10	20	1	5%
12	20	4	20%
24	20	9	45%
36	20	16	80%
48	20	14	70%
60	20	15	75%
72–120	40	39	97%
132–180	40	33	82%

Table 2. Fitting coefficients and statistical test of model 1

	Coefficient	t	P>|t|	95% CI
a1	0.72	0.55	<0.01	[0.61, 0.83]
a2	0.46	0.07	<0.01	[0.31, 0.61]
b1	0.85	0.02	<0.01	[0.80, 0.90]
b2	−0.17	0.03	<0.01	[−0.24, −0.11]
b3	23.00	1.44	<0.01	[20.1, 26]

Figure 1. Theoretical and actual prevalence of EV71 generated by model 1.

Figure 2. Theoretical and actual prevalence of EV71 generated by model 2.